Synthesis of alpha-Kdo-(2----4)-Kdo disaccharide derivatives and their conjugation with a protected form of GLA-60, a biologically active analog of a lipid A subunit.

DOI: 10.1016/0008-6215(90)84106-5

Source and publish data:

Carbohydrate research p. 59 - 73 (1990)

Update date:2022-08-02

Topics:

Authors:

Kiso Kiso

Fujita Fujita

Ogawa Ogawa

Ishida Ishida

Hasegawa

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Article abstract of DOI:10.1016/0008-6215(90)84106-5

A variety of the protected O-[(3-deoxy-alpha-D-manno-2-octulopyranosyl)onic acid]-(2----4)-3-deoxy-D-manno-2-octulosonic acid [alpha-Kdo-2(2----4)-Kdo] derivatives have been synthesized starting from methyl [2-(trimethylsilyl)ethyl 4,5,7,8-tetra-O-acetyl-

Full text of DOI:10.1016/0008-6215(90)84106-5

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Product name:Benzyl 2-O-acetyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-D-manno-2-octulopyranosonate

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