Tetrahedron Letters p. 2157 - 2160 (1990)
Update date:2022-08-05
Topics:
Solladie-Cavallo, A.
Bencheqroun, M.
The lithium anion of N-isopropyl-N-methyl formamidine 1b reacts with aldehydes in yields up to 95percent leading to the less substituted addition-products, and thus provides a short synthesis (3 steps) of propanolol, an bioactive amino-alcohol.
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Doi:10.1021/ol200744s
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