Tetrahedron p. 3813 - 3818 (1990)
Update date:2022-08-04
Topics:
Teshima, Tadashi
Matsumoto, Takahiro
Wakamiya, Tateaki
Shiba, Tetsuo
Nakajima, Terumi
Kawai, Nobufumi
In a study on structure-activity relationship of spider toxin NSTX-3 obtained from venom of Nephila maculata, nine analogs or fragments of natural toxin were synthesized.Among them, des-Arg-NSTX-3 was found to be the minimum structure for blocking the excitatory transmission in the crustacean neuromuscular synapse.A positive charge of the arginine part was concluded to play the most important role for exhibition of the activity.
View MoreNanyang Tianhua pharmaceutical Co.,Ltd.
Contact:+8618639816203
Address:Longsheng Industrial Park
Contact:+86-710-3516804
Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei
Changzhou Ruiping Chemical Co., Ltd
website:http://www.wishchem.com
Contact:+86-519-82324280
Address:No.288-1 Huacheng Road, Jintan
Nantong Kaixin Pharma Chemical Co.,Ltd.
Contact:86-513-85250786
Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Linyi Shengxin Pharmaceutical R&D Co., Ltd
Contact:+86-18653953873
Address:West First of Yufeng Road, Yishui County
Doi:10.1021/ol200659c
(2011)Doi:10.1021/jm101182s
(2011)Doi:10.1016/j.ejmech.2014.02.013
(2014)Doi:10.1016/j.tet.2011.02.064
(2011)Doi:10.1021/acs.joc.7b00697
(2017)Doi:10.1055/s-1990-26907
(1990)
