Remote functionalisation via sodium alkylamidozincate intermediates: Access to unusual fluorenone and pyridyl ketone reactivity patterns

Article abstract of DOI:10.1039/c1cc10193e

Treating fluorenone or 2-benzoylpyridine with the sodium zincate [(TMEDA)·Na(μ-^tBu)(μ-TMP)Zn(^tBu)] in hexane solution, gives efficient ^tBu addition across the respective organic substrate in a highly unusual 1,6-fashion, p