Nano-TiO 2: An eco-friendly and clean reusable heterogeneous catalyst for preparation of α-aminophosphonates under ambient and solvent-free conditions

Article abstract of DOI:10.1080/10426507.2012.717135

A one-pot catalytic three-component synthesis of α-aminophosphonates from arylaldehydes, anilines, and triethylphosphite by employing TiO₂ nanoparticles as a catalyst is described. Nano-TiO₂ has been found to be an excellent catalyst for the green synthesis of α-aminophosphonates under ambient and solvent-free conditions. This green and mild nano catalytic procedure showed good recyclability and provides cleaner conversion in a short reaction time. These advantages make the protocol feasible and economically attractive for researchers.