Journal of Organic Chemistry p. 5448 - 5450 (1990)
Update date:2022-08-04
Topics:
Askin, D.
Reamer, R. A.
Joe, Daisy
Volante, R. P.
Shinkai, I.
The novel sarcosine 2 and proline 3 (FK-525) analogues of FK-506 have been synthesized.Allylic rearranged products not observed in the pipecolinic acid series have been isolated from the amino acid formation/macrocyclization step.
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