Australian Journal of Chemistry p. 375 - 381 (1990)
Update date:2022-08-05
Topics:
Donati, Cosimo
Hung, Tran V.
Prager, Rolf H.
Phthalide-3-carboxylic acid has been decarboxylated in the presence of isoquinoline, 1-chloroisoqinoline and isoquinoline N-oxides to give low yields of compounds resulting from alkylation of the isoquinoline heterocycle at C1 with a phthalidyl group.Attempted Barton decarboxylation-alkylation in the presence of isoquinolinium salts was unsuccessful.
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