Synthesis of some C-8-modified 3-deoxy-beta-D-manno-2-octulosonic acid analogs as inhibitors of CMP-Kdo synthetase.

DOI: 10.1016/0008-6215(90)84236-N

Source and publish data:

Carbohydrate research p. 185 - 207 (1990)

Update date:2022-08-02

Topics: Synthesis Inhibitors Analog

Authors:

Tadanier

Lee Lee

Whittern

Wideburg

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Article abstract of DOI:10.1016/0008-6215(90)84236-N

Selective C-8 modifications of 2,6-anhydro-3-deoxy-D-glycero-D-talo-octonic acid ("2,3-dideoxy-beta-D-manno-2-octulosonic acid", 1a) were effected via the protected 8-hydroxy derivatives 2d and 2e. Swern oxidation of 2d and 2e gave the aldehydes 3a and 3b

Full text of DOI:10.1016/0008-6215(90)84236-N

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Product name:methyl 2,6-anhydro-8-O-benzoyl-3-deoxy-D-glycero-D-talo-octonate

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