Chemistry Letters p. 905 - 908 (1990)
Update date:2022-08-04
Topics:
Saigo, Kazuhiko
Shimada, Shigeru
Hasegawa, Masaki
In the presence of titanium(IV) chloride, ethyl 2,2-dialkoxycyclopropanecarboxylates reacted with imines to give γ-lactams.Especially, when N-tosyl aldimines were employed, cis-3,4-disubstituted γ-lactams were obtained in good yields with high diastereoselectivity.
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Doi:10.1016/j.materresbull.2012.02.015
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(2011)
