SYNTHETIC STUDIES ON MANZAMINE A II; A NOVEL DIELS-ALDER APPROACH TO THE PYRROLOISOQUINOLINE SKELETON

DOI: 10.1016/S0040-4039(00)94730-0

Source and publish data:

Tetrahedron Letters p. 3195 - 3198 (1990)

Update date:2022-09-26

Topics: Synthetic studies Diels-Alder approach

Authors:

Torisawa, Yasuhiro

Nakagawa, Masako

Arai, Hitoe

Lai, Ziping

Hino, Tohru

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)94730-0

An expeditious preparation of the central pyrroloisoquinoline skeleton of manzamine A (1) was achieved via the high-pressure Diels-Alder reaction of 3-alkyl-5,6-dihydro-2-pyridinone (10) with Danishefsky diene followed by deprotection and spontaneous pyrr

Full text of DOI:10.1016/S0040-4039(00)94730-0

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