A practical synthesis of optically active platelet-activating factor antagonist, (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tet rahydro-8H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]dia zepine (E6123), and its absolu

DOI: 10.1248/cpb.40.521

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 521 - 523 (1992)

Update date:2022-08-03

Topics:

Authors:

Miyazawa

Okano Okano

Shimomura

Kawahara

Asano Asano

Yoshimura

Kawai Kawai

Souda Souda

Yoshida Yoshida

Sato Sato

Machida Machida

Yamatsu Yamatsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.521

Optically active platelet-activating factor (PAF) receptor antagonist, (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tet rahydro-8 H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine (E6123), was synthesized on a lar

Full text of DOI:10.1248/cpb.40.521

NII-Electronic Library Service

Products guided by the article

Product name:(-)-6-(2-chlorophenyl)-8,11-dimethyl-2,3,4,5-tetrahydro-8H-pyrido<4',3':4,5>thieno<3,2-f><1,2,4>triazolo<4,3-a><1,4>diazepine

Cas No:130311-76-1

R&D Labs maybe for 130311-76-1

VanderArk International Limited

Contact:86-10-82437576

Address:Qing He
Guangzhou Shiny Co., Ltd.

website:https://www.sinoshiny.com/products

Contact:+86-20-62802632;62802633

Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Shanghai Forever Synthesis Co.,Ltd.

Contact:021-61124658

Address:Zhoukang Road,Pudong New District,Shanghai,China
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China

Relevant to this article

A redox series of aluminum complexes: Characterization of four oxidation states including a ligand biradical state stabilized via exchange coupling

Doi:10.1021/ja2015718
(2011)
A highly stereoselective approach to tetrasubstituted (E)-β-hydroxy silyl enol ethers by addition of aryl-substituted oxiranyl anions to acylsilanes

Doi:10.1016/j.tetlet.2011.02.108
(2011)
Thiophene systems. 12. Analogues of ketanserin and ritanserin as selective 5-HT₂ antagonists

Doi:10.1016/0223-5234(91)90007-A
(1991)
NOVEL BROMOLACTONIZATION USING A DIMETHYL SULFOXIDE-TRIMETHYLSILYL BROMIDE-AMINE SYSTEM; UNUSUAL CIS-ADDITION OF TRANS-6-SUBSTITUTED 3-CYCLOHEXENE-1-CARBOXYLIC ACIDS

Doi:10.3987/COM-90-5374
(1990)
β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase

Doi:10.1016/j.bmc.2011.02.012
(2011)
The first solid phase synthesis of pincer palladium complexes

Doi:10.1039/c1dt10680e
(2011)

Article Doi