Synthesis of macrocycles via allylic radical intermediates. A total synthesis of (-)-zearalenone

Article abstract of DOI:10.1016/S0040-4039(00)94465-4

A concise synthesis of optically active (-)-zearalenone (1) which uses a novel 14-endo trig macrocyclisation from an allylic radical intermediate (Scheme 1) as a key feature, is described.