Asymmetric synthesis of 2-Aminonorbornane-2-carboxylic acids by Diels-Alder reaction

Article abstract of DOI:10.1016/S0957-4166(00)86334-X

Reaction of (-)-menthyl N-acetyl-α,β-dehydroalaninate with cyclopentadiene takes place with good chemical yields and diastereofacial selectivity. The cycloadducts are easily transformed into the corresponding amino acids.