Efficient synthesis of optically active cis-endo-2,3-dihydroxymethyl-5-norbornene monoacetate by lipase-catalyzed transesterification

DOI: 10.1248/cpb.40.2610

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2610 - 2613 (1992)

Update date:2022-08-03

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Authors:

Murata Murata

Uchida Uchida

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.40.2610

Chiral cis-endo-2,3-dihydroxymethyl-5-norbornene monoacetate was produced by lipase-catalyzed asymmetric transesterification, and used to synthesize an optically active thromboxane A₂ (TXA₂) antagonist.

Full text of DOI:10.1248/cpb.40.2610

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