Syntheses and Biological Activities of Potent Potassium Channel Openers Derived from (+/-)-2-Oxo-1-pyridin-3-yl-cyclohexanecarbothioic Acid Methylamide: New Potassium Channel Openers

DOI: 10.1021/jm00063a010

Source and publish data:

Journal of Medicinal Chemistry p. 1604 - 1612 (1993)

Update date:2022-08-02

Topics:

Authors:

Brown, Thomas J.

Chapman, Robert F.

Mason, Jonathan S.

Palfreyman, Malcolm N.

Vicker, Nigel

Walsh, Roger J.A.

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Article abstract of DOI:10.1021/jm00063a010

The syntheses and biological activities of (+/-)-2-(cyanomethylene)-1-pyridin-3-ylcyclohexanecarbothioic acid methylamide (6) and trans-(+/-)-2-(cyanomethyl)-1-pyridin-3-ylcyclohexanecarbothioic acid methylamide (14) derived from (+/-)-2-oxo-1-pyridin-3-y

Full text of DOI:10.1021/jm00063a010

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