Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2-imidazolidinones

DOI: 10.1021/jm00105a045

Source and publish data:

Journal of Medicinal Chemistry p. 291 - 298 (1991)

Update date:2022-08-03

Topics:

Authors:

Saccomano

Vinick Vinick

Koe Koe

Nielsen Nielsen

Whalen Whalen

Meltz Meltz

Phillips

Thadieo Thadieo

Jung Jung

Chapin Chapin

Lebel Lebel

Russo Russo

Helweg Helweg

Johnson Jr.

Ives Ives

Williams

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Article abstract of DOI:10.1021/jm00105a045

The synthesis and biological properties of a novel series of selective calcium-independent phosphodiesterase inhibitors are described. These compounds also inhibit the specific binding of [³H]rolipram to rat brain membranes and exhibit efficacy

Full text of DOI:10.1021/jm00105a045

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