Fluorinated cyclitols. An improved synthesis of 5-deoxy-5-fluoro-myo-inositol, its deuterium labeling, and synthesis of a 5,5-gem-difluoro analogue

DOI: 10.1016/0008-6215(90)84054-X

Source and publish data:

Carbohydrate Research p. 277 - 285 (1990)

Update date:2022-08-04

Topics:

Authors:

Jiang, Cong

Schedler, David J. A.

Morris, Philip E.

Zayed, Abdel-Hadi A.

Baker, David C.

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Article abstract of DOI:10.1016/0008-6215(90)84054-X

An improved synthesis of 5-deoxy-5-fluoro-myo-inositol is provided via the reaction of diethylaminosulfur trifluoride (DAST) with the versatile intermediate, 1,4,6-tri-O-benzyl-2,3-O-cyclohexylidene-neo-inositol (I), followed by appropriate deprotection r

Full text of DOI:10.1016/0008-6215(90)84054-X

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