Synthesis of Doubly Bridgehead Substituted Bicyclopentanes. Radical Transformations of Bridgehead Halides and Carboxylic Acids

Article abstract of DOI:10.1021/jo00001a058

Synthetic transformations of the 1-bicyclo<1.1.1>pentyl bridgehead radicals 11 generated from the corresponding bridgehead iodides 3 and carboxilic acids 5 are described.The relatively high nucleophilicity of these radicals was utilized in reactions with