NEW SYNTHESIS OF 4-ACETOXY-2-AZETIDINONES BY USE OF ELECTROCHEMICAL OXIDATION

DOI: 10.1016/S0040-4020(01)87042-3

Source and publish data:

Tetrahedron p. 531 - 540 (1991)

Update date:2022-08-04

Topics:

Authors:

Mori, Miwako

Kagechika, Katsuji

Sasai, Hiroaki

Shibasaki, Masakatsu

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Article abstract of DOI:10.1016/S0040-4020(01)87042-3

4-Acetoxy-2-azetidinone was synthesized from 4-carboxy-2-azetidinone by Kolbe-type electrolysis.Optically pure 4-acetoxy-3-<1-(t-butyldimethylsiloxy)ethyl>-2-azetidinone, which is an important intermediate for the synthesis of thienamycin, and (+)-PS-5 were synthesized by use of this method.

Full text of DOI:10.1016/S0040-4020(01)87042-3

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