Bioscience, Biotechnology and Biochemistry p. 246 - 248 (2007)
Update date:2022-08-05
Topics:
Iwai, Noritaka
Fujii, Takuya
Nagura, Hirokatsu
Wachi, Masaaki
Kitazume, Tomoya
We comprehensively investigated the effects of substitution of the benzyl group in S-benzylisothiourea derivatives on antibacterial activity, because we found previously that some substitutions enhanced it. A 2,4-Cl 2-derivative was found to be the most effective compound, it was stronger than the original one in Gram-negative rod shaped-bacteria such as Escherichia coli and Salmonella typhimurium.
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