Enantioselective Synthesis of the Bottom Half of Chlorothricolide. 2. A Comparative Study of Substituent Effects on the Stereoselectivity of the Key Intramolecular Diels-Alder Reaction

DOI: 10.1021/jo00238a049

Source and publish data:

Journal of Organic Chemistry p. 710 - 712 (1988)

Update date:2022-08-05

Topics:

Authors:

Roush, William R.

Riva, Renata

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Article abstract of DOI:10.1021/jo00238a049

The intramolecular Diels-Alder reactions of trienes 4-7 were studied to evaluate the ability of diene (TMS, Br) and dienophile (CHO, CO2Me) substituents to influence Diels-Alder stereoselectivity and thereby define the optimal precursor to the bottom half of chlorothricolide.

Full text of DOI:10.1021/jo00238a049

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