Biomimetic studies using artificial systems. VI. Design and synthesis of novel cyclophanes having eight carboxyl groups on the aromatic rings

DOI: 10.1248/cpb.41.1211

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1211 - 1213 (1993)

Update date:2022-08-03

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Authors:

Miyake Miyake

Kirisawa

Koga Koga

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Article abstract of DOI:10.1248/cpb.41.1211

Novel cyclophanes (9a, b) having eight carboxyl groups on the aromatic rings were designed and synthesized. Macrocyclization of 7a and 7b with 6 was carried out under a high dilution condition to give the corresponding 8a and 8b in 23% and 28% yields, respectively.

Full text of DOI:10.1248/cpb.41.1211

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