Journal of Medicinal Chemistry p. 984 - 992 (1991)
Update date:2022-08-04
Topics:
Klein, Larry L.
Yeung, Clinton M.
Chu, Daniel T.
McDonald, Edith J.
Clement, Jacob J.
Plattner, Jacob J.
Several ring-contracted analogues of the antitumor agent etoposide have been prepared.The synthesis of the simple indanyl system 3 is described along with two bicyclic systems of general structure 4 prepared through a stereoselective allylation of the ket
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