Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues

DOI: 10.1021/jm00108a026

Source and publish data:

Journal of Medicinal Chemistry p. 1415 - 1421 (1991)

Update date:2022-08-04

Topics:

Authors:

Bisacchi

Braitman

Cianci Cianci

Clark Clark

Field Field

Hagen Hagen

Hockstein

Malley Malley

Mitt Mitt

Slusarchyk

Sundeen Sundeen

Terry Terry

Tuomari Tuomari

Weaver Weaver

Young Young

Zahler Zahler

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Article abstract of DOI:10.1021/jm00108a026

The syntheses of the enantiomeric cyclobutyl guanine nucleoside analogues [1R-1α,2β,3α]- and [1S-1α,2β,3α]-2-amino-9-[2,3-bis(hydroxymethyl) cyclobutyl]-6H-purin-6-one (7 and 8, respectively) and the enantiomeric cyclobutyl adenine analogues [1R-1α,2β,3α]

Full text of DOI:10.1021/jm00108a026

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Product name:<1S-<1α(S^*),2β(S^*)>>-3,3-diethoxy-N,N'-bis-(2-hydroxy-1-phenylethyl)-1,2-cyclobutanedicarboxamide

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