2-Propynylamines from 1,1-Dibromo-1-alkenes

Article abstract of DOI:10.1055/s-1990-27057

Easily accessible 1,1-dibromo-1-alkenes react with primary or secondary amines in a complex series of reactions to give directly N-substituted or N,N-disubstituted (1-Alkyl-1-aryl-2-propynyl)amines 5 in useful yields.This simple method avoids the isolation of intermediates (bromoacetylenes or bromoallenes) and makes a series of 2-propynylamines with an acetylenic hydrogen available.