Synthesis and pharmacological activities of some 3-substituted thienopyrimidin-4-one-2-thiones

Article abstract of DOI:10.1016/0223-5234(90)90128-P

The condensation of substituted 2-amino-3-carbethoxy-thiophenes with methyl, ethyl and phenyl isothiocyanate yields the corresponding thienylthioureas which cyclize in ethanol saturated with dry hydrochloric acid to form 3-substituted thieno<2,3-d>pyrimid