Journal of Medicinal Chemistry p. 2040 - 2048 (1992)
Update date:2022-08-04
Topics:
Barker, Peter L.
Bullens, Sherron
Bunting, Stuart
Burdick, Daniel J.
Chan, Kathryn S.
et al.
Stimulation of platelets activates GPIIbIIIa, the heterodimeric integrin receptor, to bind fibrinogen (Fg), which results in platelet aggregation.GPIIbIIIa/Fg binding inhibitors are potentially suitable for acute use during and after thrombolytic therapy
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