Journal of Medicinal Chemistry p. 1049 - 1062 (1991)
Update date:2022-08-05
Topics:
Sih, John C.
Im, Wha Bin
Robert, Andre
Graber, David R.
Blakeman, David P.
The synthesis of N-substituted benzimidazole (H+-K+)-ATPase or proton-pump inhibitors is described.These compounds were prepared to function as prodrugs of the parent N-H compound and evaluated for their ability to inhibit gastric (H
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