Synthesis of potential Naftopidil metabolites

DOI: 10.1002/ardp.19933261007

Source and publish data:

Archiv der Pharmazie p. 803 - 806 (1993)

Update date:2022-08-05

Topics:

Authors:

Kutscher

Engel Engel

Fleischhauer

Niebch Niebch

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ardp.19933261007

The synthesis of four proposed metabolites 1-4 of Naftopidil, a selective α₁-antagonist, is reported. These compounds comprise hydroxylated and demethylated derivatives and a cleavage product of Naftopidil.

Full text of DOI:10.1002/ardp.19933261007

Products guided by the article

Product name:(Phenyl)hydroxynaftopidil

Cas No:133024-35-8

R&D Labs maybe for 133024-35-8

LINYI FUDE FINE CHEMICAL CO.,LTD

Contact:86-539-2361184

Address:YISHUI, LINYI,SAHNDONG,CHINA
Esuccess Material Limited

Contact:852-29282288

Address:HONGKONG
Jai Radhe Sales

website:http://www.jairadhesales.com

Contact:0091-79-26431096

Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
VanderArk International Limited

Contact:86-10-82437576

Address:Qing He
Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang

Relevant to this article

Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes

Doi:10.1016/j.tetlet.2011.03.063
(2011)
Core chemotype diversification in the HIV-1 entry inhibitor class using field-based bioisosteric replacement

Doi:10.1016/j.bmcl.2015.10.080
(2016)
Construction of carbocyclic ring of indoles using ruthenium-catalyzed ring-closing olefin metathesis

Doi:10.1021/ol201510u
(2011)
Doi:10.1016/S0024-3205(00)00557-9
(1951)
Functionalization of some benzylthioarylboronic acids by benzylic lithiation of their N-butyldiethanolamine esters or lithium (triisopropoxy) borates

Doi:10.1002/aoc.1822
(2011)
Iron-catalyzed direct α-arylation of ethers with azoles

Doi:10.1039/c5cc05005g
(2015)

Article Doi