Journal of the Chemical Society. Chemical communications p. 1647 - 1648 (1990)
Update date:2022-08-03
Topics:
Kruizinga, Wim H.
Kingma, Rob
Leegstra, Libbe
Rokaszewski, Edward
Gruppen, Gert
Kellogg, Richard M.
Three di-, (Gly)2, (Val)2 and (Leu)2, and one tetrapeptide, (Gly)4, have been acylated with 2-chloroacetyl chloride and the resulting products treated with Cs2CO3 in the dimethylformamide (DMF) solution; (Gly)2 and (Leu)2 provided strained 9-membered rings whereas (Val)2 dimerized to the 18-membered ring.
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