Silicon directed diastereo- and enantioselective Mukayama Michael tandem aldol condensation: A novel strategy for six membered ring cyclisation

Article abstract of DOI:10.1016/S0040-4039(00)88542-1

Silicon directed diastereo- and enantioselective conjugate addition of enolsilanes to α,β-unsaturated ketones are reported which undergo subsequent intramolecular cyclization on treatment with aqueous HBF₄ to furnish aldol adducts. Depending on