Cross-coupling of mesylated phenol derivatives with potassium cyclopropyltrifluoroborate

Article abstract of DOI:10.1021/jo2015246

C-O activation of mesylates by a palladium catalyst and subsequent cross-coupling with potassium cyclopropyltrifluoroborate have been achieved with high yield. Both electron-enriched and electron-deficient aryl mesylates are suitable electrophilic partners for the Suzuki-Miyaura reaction. The scope was successfully extended to heteroaryl mesylates with yields up to 94%. (Figure presented)