New Bronchodilators. 1. 1,5-Substituted 1H-Imidazoquinolin-4(5H)ones

DOI: 10.1021/jm00100a009

Source and publish data:

Journal of Medicinal Chemistry p. 4045 - 4053 (1992)

Update date:2022-08-04

Topics: New 1,5-Substituted

Authors:

Suzuki, Fumio

Kuroda, Takeshi

Nakasato, Yoshisuke

Manabe, Haruhiko

Ohmori, Kenji

et al. et al.

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Article abstract of DOI:10.1021/jm00100a009

A series of novel xanthine-based tricyclic heterocycles in 1H-imidazo<4,5-c>quinolin-4(5H)-ones was designed, synthesized, and tested as potential active bronchodilators.Inhibition of the Schulz-Dale (SD) reaction-induced contraction in trachea and inhibi

Full text of DOI:10.1021/jm00100a009

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