Journal of Medicinal Chemistry p. 4045 - 4053 (1992)
Update date:2022-08-04
Topics: New 1,5-Substituted
Suzuki, Fumio
Kuroda, Takeshi
Nakasato, Yoshisuke
Manabe, Haruhiko
Ohmori, Kenji
et al.
A series of novel xanthine-based tricyclic heterocycles in 1H-imidazo<4,5-c>quinolin-4(5H)-ones was designed, synthesized, and tested as potential active bronchodilators.Inhibition of the Schulz-Dale (SD) reaction-induced contraction in trachea and inhibi
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