Enantiospecific and diastereoselective synthesis of C11-C17 fragment of tylonolide from "asymmetrized tris (hydroxymethyl)methane"

Article abstract of DOI:10.1016/0040-4039(91)80872-4

The fragment C₁₁-C₁₇ of tylonolide 2 was straightforwardly and stereoselectively synthesized starting from monoacetate 5, which is a synthetic equivalent of "asymmetrized tris (hydroxymethyl)methane" 3.