Total synthesis of bryostatins: The development of methodology for the atom-economic and stereoselective synthesis of the ring C subunit

DOI: 10.1002/chem.201002898

Source and publish data:

Chemistry - A European Journal p. 9762 - 9776 (2011)

Update date:2022-09-26

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Authors:

Trost, Barry M.

Frontier, Alison J.

Thiel, Oliver R.

Yang, Hanbiao

Dong, Guangbin

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Article abstract of DOI:10.1002/chem.201002898

Bryostatins, a family of structurally complicated macrolides, exhibit an exceptional range of biological activities. The limited availability and structural complexity of these molecules makes development of an efficient total synthesis particularly impor

Full text of DOI:10.1002/chem.201002898

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