Addition of Glycinate Enolate Equivalents to 1,4-Benzodiazepine Imino Phosphates. Preparation of Synthetically Useful 2-(Ethyl glycinat-α-ylidene)-1,4-benzodiazepines and Related Derivatives

DOI: 10.1021/jo00011a051

Source and publish data:

Journal of Organic Chemistry p. 3715 - 3719 (1991)

Update date:2022-08-02

Topics: Yield   NMR spectroscopy   Catalyst   Electrophile   Deprotonation   Chromatography   Mass spectrometry (MS)   Nucleophilic addition   Derivative   Workup   Reaction Mechanism   Phosphorylation   Reaction Optimization   Synthetic Utility   1,4-benzodiazepine   Solvent system  

Authors:

Fryer, R. Ian

Kudzma, Linas V.

Gu, Zi-Qiang

Lin, Kuei-Ying