Synthesis, antimicrobial activity and possible mechanism of action of 9-bromo-substituted indolizinoquinoline-5,12-dione derivatives

DOI: 10.1016/j.ejmech.2011.07.042

Source and publish data:

European Journal of Medicinal Chemistry p. 4625 - 4633 (2011)

Update date:2022-07-29

Topics:

Authors:

Wu, Xi-Wei

Wu, Zu-Ping

Wang, Lu-Xia

Zhang, Hong-Bin

Chen, Jian-Wen

Zhang, Wei

Gu, Lian-Quan

Huang, Zhi-Shu

An, Lin-Kun

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Article abstract of DOI:10.1016/j.ejmech.2011.07.042

A series of 9-bromo-substituted indolizinoquinoline-5,12-dione derivatives was synthesized. Antimicrobial activity assessment indicates that compounds 1, 26, 27 and 28 exhibit strong activity against gram-positive bacterial strains, including Beta-hemolyt

Full text of DOI:10.1016/j.ejmech.2011.07.042

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Product name:N-benzyl-9-bromo-5,12-dioxo-5,12-dihydroindolizino[2,3-g]quinoline-6-carboxamide

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