Substituent Effect on the Stereochemistry of H2-Receptor Antagonists of the Phenylformamidine Series. A Conformation-Dependent Mode of Interaction with the H2 Receptor

DOI: 10.1021/jm00110a004

Source and publish data:

Journal of Medicinal Chemistry p. 1772 - 1776 (1991)

Update date:2022-08-03

Topics:

Authors:

Donetti, Arturo

Bastiaans, Harold M. M.

Kramer, Klaas

Bietti, Giuseppe

Cereda, Enzo

et al. et al.

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Article abstract of DOI:10.1021/jm00110a004

The influence of alkyl substitution on the stereoisomerism of the formamidine cation (E,E vs E,Z) of several N-substituted (imidazolylphenyl)formamidines (1-10) was investigated.As (imidazolylphenyl)formamidines having alkyl substituents of more than thre

Full text of DOI:10.1021/jm00110a004

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Product name:Methanimidamide, N-(1-ethylpropyl)-N'-[4-(1H-imidazol-4-yl)phenyl]-, dihydrochloride

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