Tetrahedron Letters p. 5973 - 5976 (1992)
Update date:2022-08-04
Topics:
Takahashi
Shimayama
Miyazawa
Nakazawa
Yamada
Takatori
Kajiwara
Preparation of an optically active synthetic intermediate 3 starting from D-mannitol and its conversion to PGF2α (1) by using [3+2] cycloaddition of the nitrile oxide derivative of 3 followed by conjugate addition of the vinylzincate to exocyclic enone 2 are described.
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