Journal of the Chemical Society. Chemical communications p. 314 - 316 (1991)
Update date:2022-08-04
Topics:
Bowler, Andrew N.
Doyle, Paul M.
Young, Douglas W.
Heterocyclic derivatives 6 of (S)-glutamic acid, which are structurally related to key central nervous system (CNS) glutamate receptor agonists,are prepared from the aldehyde 9 using a novel reaction in which the pyroglutamate ring is cleaved in concert with formation of the new heterocyclic ring.
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