C10 N-Acyl modified KY-506: A possible hybrid analogue of the transition state of peptidyl-prolyl cis-trans isomerization

DOI: 10.1016/S0040-4039(00)79671-7

Source and publish data:

Tetrahedron Letters p. 1375 - 1378 (1991)

Update date:2022-08-02

Topics:

Authors:

Donald Donald

Cooper Cooper

Furber Furber

Wells Wells

Hutchinson

Black Black

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Article abstract of DOI:10.1016/S0040-4039(00)79671-7

Three C 10 N-Acyl derivatives of FK-506 have been prepared. The reduced receptor binding of these analogues is not consistent with a direct overlap of FK-506 and a peptide substrate.

Full text of DOI:10.1016/S0040-4039(00)79671-7

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