Highly selective reactions of FK506 with diazomethane

DOI: 10.1016/0040-4039(91)85034-3

Source and publish data:

Tetrahedron Letters p. 7039 - 7042 (1991)

Update date:2022-08-03

Topics:

Authors:

Edmunds Edmunds

Baumann Baumann

Grassberger

Schulz Schulz

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Article abstract of DOI:10.1016/0040-4039(91)85034-3

Three modes of diazomethane reactivity, namely oxirane formation, O-methylation and cyclopropanation, can be accomplished with excellent selectivity on the multifunctional molecule FK506.

Full text of DOI:10.1016/0040-4039(91)85034-3

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