Synthesis, Stereochemistry, and Biological Activity of the 1-(1-Phenyl-2-methylcyclohexyl)piperidines and the 1-(1-Phenyl-4-methylcyclohexyl)piperidines. Absolute Configuration of the Potent trans-(-)-1-(1-Phenyl-2-methylcyclohexyl)piperidine

DOI: 10.1021/jm00112a041

Source and publish data:

Journal of Medicinal Chemistry p. 2615 - 2623 (1991)

Update date:2022-09-26

Topics:

Authors:

Iorio, Maria A.

Tomassini, Lamberto

Mattson, Mariena V.

George, Clifford

Jacobson, Arthur E.

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Article abstract of DOI:10.1021/jm00112a041

The (-)- and (+)-isomers of the cis- and trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)piperidines have been synthesized and the achiral cis- and trans-Ph/Me 1-(1-phenyl-4-methylcyclohexyl)piperidines were prepared, and their in vitro TC

Full text of DOI:10.1021/jm00112a041

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Product name:cis-CN/Me 1-(1-piperidinyl)-2-methylcyclohexanecarbonitrile

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