Design, synthesis and systematic evaluation of all possible cyclic dinucleotides (CDNs) that activate human stimulator of interferon genes (STING) variants

DOI: 10.1007/s11426-019-9662-5

Source and publish data:

Science China Chemistry (2020)

Update date:2022-07-30

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Authors:

Li, Lu-Yuan

Ma, De-Jun

Wang, Chuan-Lin

Wang, Da-Wei

Wang, Zheng-Hua

Wen, Xin

Xi, Zhen

Zhang, Hang

Zhang, Qiang-Zhe

Zhao, Can-Can

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Article abstract of DOI:10.1007/s11426-019-9662-5

Cyclic dinucleotides (CDNs) are known to activate stimulator of interferon genes (STING) and induce type I interferon responses, therefor possess great potentials to be of immunotherapeutic value for cancers and infectious diseases. However, the existence

Full text of DOI:10.1007/s11426-019-9662-5

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