Synthesis and Biological Activity of Angiotensin II Analogues Containing a Val-His Replacement, ValΨHis

DOI: 10.1021/jm00112a014

Source and publish data:

Journal of Medicinal Chemistry p. 2402 - 2410 (1991)

Update date:2022-08-04

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Authors:

Mohan, Raju

Chou, Yuo-Ling

Bihovsky, Ron

Lumma, William C.

Erhardt, Paul W.

Shaw, Kenneth J.

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Article abstract of DOI:10.1021/jm00112a014

The dipeptide mimic ValΨHis (4) was incorporated into angiotensin II (AII) analogues to provide an octapeptide saralisn derivative (29) as well as tetrapeptide analogue 19.Three C-terminal tetrapeptides (21, 25, and 28) were also prepared.All

Full text of DOI:10.1021/jm00112a014

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