Tetrahedron Letters p. 1535 - 1538 (1991)
Update date:2022-07-30
Topics:
Wei
Bakthavatchalam
The first solid state aldol addition of the lithium enolate of methyl 3,3-dimethylbutanoate to aromatic aldehydes is reported. The diastereoselectivity of the reactions in the solid state is similar to that in solution, suggesting that the same reacting species and transition states might be involved.
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