Synthesis p. 277 - 278 (1991)
Update date:2022-07-29
Topics:
Shestopalov
Bogomolova
Litvinov
Interaction of 1-(1-adamantylcarbonylmethyl)pyridinium bromide (1) with arylmethylenecyanothioacetamides 2 proceeds stereoselectively with formation of 2-(1-adamantylcarbonyl)-5-amino-3-aryl-4-cyano-2,3-dihydrothiophenes. Dihydrothiophenes were obtained in a good yield by three-component condensation of pyridinium bromide 1, aldehydes and cyanothioacetamide in presence of triethylamine.
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Doi:10.1021/acsmedchemlett.5b00402
(2016)Doi:10.1039/c1ob06038d
(2011)Doi:10.1016/S0040-4020(01)96113-7
(1991)Doi:10.1021/jo00053a056
(1993)Doi:10.1016/j.bmcl.2015.05.082
(2015)Doi:10.1246/bcsj.64.1129
(1991)