Helvetica Chimica Acta p. 531 - 542 (1991)
Update date:2022-08-06
Topics:
Pascual, Alfons
Substitued N-(isoxazol-4-yl)thioureas 1 undergo a transformation in the presence of hexacarbonylmolybdenum and acid to yield functionalized thiazoles 3 in a one-pot reaction. In a few cases, 1,4,5-trisubstituted dihydroimidazoleth, iones 4 are also isolated as side products. Mechanistic considerations are outlined and scope and limitations of this new methodology discussed.
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(2011)Doi:10.1039/c39910000375
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(2011)Doi:10.1021/jm201226w
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(1994)