CYCLIZATION OF FLUOROALKYL-CONTAINING 1,3-DICARBONYL COMPOUNDS WITH ETHYLENEDIAMINE HYDROPERCHLORATE TO 1,4-DIAZEPINES

Article abstract of DOI:10.1007/BF00958575

2,3-Dihydro-1H-1,4-diazepines and 1,2,3,4-tetrahydro-1,4-diazeptin-5-ones were obtained by direct condensation of fluorine-containing 1,3-diketones and 1,3-keto ethers, respectively, with ethylenediamine monohydroperchlorate.The structure of the compounds was confirmed by 1H NMR, mass spectrometry and molecular weight determination.