A facile synthesis of functionalized 4-benzylpyridines by using mixed copper, zinc benzylic organometallics

DOI: 10.1016/S0040-4039(00)78900-3

Source and publish data:

Tetrahedron Letters p. 2033 - 2034 (1991)

Update date:2022-07-30

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Authors:

Chia Chia

Shiao Shiao

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Article abstract of DOI:10.1016/S0040-4039(00)78900-3

A general approach by use of highly functionalized mixed copper zinc, benzylic organometallics to react with N-ethoxycarbonylpyridinium chloride to give regioselectively 4-benzylpyridines after oxygen oxidation in 30-75% yield is described.

Full text of DOI:10.1016/S0040-4039(00)78900-3

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